Myocardial Protection Strategies During Cardiac Surgery: A Comprehensive Review
Review
DOI:
https://doi.org/10.5281/zenodo.11076486Keywords:
Cardiac Surgery, Myocardial Protection Strategies, PerfusionAbstract
Cardiac surgery is a complex and delicate procedure that requires careful planning and execution to ensure favourable patient outcomes. One of the most critical aspects of cardiac surgery is myocardial protection, which aims to minimise damage to the heart muscle during the operation. In this comprehensive review, we will examine the various myocardial protection strategies used during cardiac surgery, their benefits and risks. We will also examine the use of cardioplegia, a technique involving the temporary suspension of cardiac function, to protect the myocardium. We will also discuss measures that can be taken to reduce ischaemia-reperfusion injury and its impact on the heart. Finally, we will examine postoperative management strategies to protect the myocardium and shorten the recovery time of patients undergoing cardiac surgery. By providing a detailed overview of these topics, this review aims to inform and assist healthcare professionals in making informed decisions about myocardial protection strategies during cardiac surgery.
References
Bradley SA. Myocardial protection: a forgotten modality, European Journal of Cardio-Thoracic Surgery. 2020;57(2):263–270. https://doi.org/10.1093/ejcts/ezz215
Derek J, Hausenloy, Edney Boston-Griffiths, Derek M. Yellon, Cardioprotection during cardiac surgery, Cardiovascular Research. 2012;94(2),253-265. https://doi.org/10.1093/cvr/cvs131
Kato, Norman S, Buckberg, Gerald D. New intraoperative cardioprotective strategies for myocardial protection. Current Opinion in Cardiology. 1992;7(6):959-967.
Xin Z, Xueyao Y, Ziyu A. Pathophysiology and molecular mechanism of caveolin involved in myocardial protection strategies in ischemic conditioning. Biomedicine & Pharmacotherapy. 2022;153:113282. https://doi.org/10.1016/j.biopha.2022.113282
George G, Varsha AV, Philip MA, et al. Myocardial protection in cardiac surgery: Del Nido versus blood cardioplegia. Ann Card Anaesth. 2020;23(4):477-484. doi:10.4103/aca.ACA_153_19
Jacob S, Kallikourdis A, Sellke F, Dunning J. Is blood cardioplegia superior to crystalloid cardioplegia?, Interactive CardioVascular and Thoracic Surgery. 2008;7(3):491-498. https://doi.org/10.1510/icvts.2008.178343
Durandy YD. Is there a rationale for short cardioplegia re-dosing intervals?. World J Cardiol. 2015;7(10):658-664. doi:10.4330/wjc.v7.i10.658
Siriussawakul A, Zaky A, Lang JD. Role of nitric oxide in hepatic ischemia-reperfusion injury. World J Gastroenterol. 2010;16(48):6079-6086. doi:10.3748/wjg.v16.i48.6079
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Anatolia Cor
This work is licensed under a Creative Commons Attribution 4.0 International License.